Ursodeoxycholic acid 128-13-2 Nidaamka dheefshiidka cholagogic
Lacag bixintaT/T, L/C
Asal ahaan badeecada:Shiinaha
Dekadda Rarida:Beijing/Shanghai/Hangzhou
Awoodda wax-soo-saarka:2000kg/bishii
Dalbo (MOQ):25kg
Waqtiga Hogaaminta:3 Maalmo Shaqo
Xaaladda kaydinta:Lagu kaydiyaa qabow, meel qalalan, heerkulka qolka.
Qalabka xirmada:durbaan
Cabbirka xirmada:25kg/durbaan
Macluumaadka badbaadada:Maaha alaab khatar ah
Hordhac
Ursodeoxycholic acid (UDCA), oo sidoo kale loo yaqaano ursodiol, waa asiidh labaad oo xariif ah, oo laga soo saaro bini'aadamka iyo inta badan noocyada kale ee dheef-shiid kiimikaadka bakteeriyada xiidmaha.Waxa uu ku dhex abuurmaa beerka noocyada qaar, waxaana markii ugu horreysay lagu aqoonsaday bile orso, kaas oo ka soo jeeda magaca Ursus.Qaab la safeeyey, waxa loo isticmaalay in lagu daweeyo ama looga hortago cudurro badan oo beerka ama xiniinyaha.
UDCA waxa loo isticmaalay daawaynta daawaynta ee cudurka xameetida (cholelithiasis) iyo biliary sludge.UDCA waxay caawisaa dhimista kolesteroolka dheecaanka xameetida waxayna keentaa in si tartiib tartiib ah u milmaan xameetida qani ku ah kolestaroolka.
UDCA waxa laga yaabaa in la siiyo qaliinka bariatric ka dib si looga hortago cholelithiasis, kaas oo caadi ahaan dhaca sababtoo ah miisaanka oo yaraada degdega ah ee soo saara kolestaroolka biliary oversaturation iyo sidoo kale biliary dyskinesia hormoonnada labaad ee isbeddelka.
Tilmaamaha (EP10)
| Shayga | Tilmaamid |
| Muuqashada | Caddaan ama ku dhawaad budo cad |
| Solubility | Dhab ahaan aan biyo ku milmin, si xor ah ugu milmay ethanol (96%), wax yar ku milma acetone, ficil ahaan aan lagu milmi karin methylene chloride |
| barta dhalaalaysa | 202-204℃ |
| Aqoonsiga | spectrum IR la mid ah sida ursodeoxycholic acid CRS |
| Meesha ugu muhiimsan ee chromatogram-ka ee lagu helay xalka tijaabada (b) waxay la mid tahay booska, midabka iyo cabbirka barta mabda'a ee chromatogram-ka ee lagu helay xal tixraaceed (a). | |
| Ka joojinta la helay waa cagaar-buluug. | |
| Wareegga indhaha ee gaarka ah | +58.0~+62.0° |
| Xumaanta C | Lithocholic acid ≤ 0.1% |
| Walaxda la xidhiidha (HPLC) | wasakh A: chenodeoxycholic acid ≤ 1.0% |
| wasakh aan la cayimin ≤ 0.1% | |
| wadarta guud ≤ 1.5% | |
| Biraha culus | ICH Q3D |
| Luminta qalajinta | ≤ 1.0% |
| dambaska sulphateed | ≤ 0.1% |
| Qiimayn | 99.0% ~ 101% (Wax qalalan) |
| Haraaga dareerayaasha | Acetone ≤ 5000 ppm Ethyl acetate ≤ 5000 ppm Isopropanol ≤ 5000 ppm Ethanol ≤ 5000 ppm |
| Tijaabooyinka Microbiological | Wadarta tirada microbial aerobic ≤ 10³CFU/g Wadarta khamiirka iyo caaryada ayaa tirinaya ≤ 10²CFU/g Escherichia coli: Maqan 1 g Salmonella: Maqan 10 g |
| Guryo dheeraad ah | |
| Qaybinta cabbirka qaybta | 100% nambarka gudbinta 180 shaandho (100% dhaaf 80 shaandho mesh ah) |
